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Hodgkin Disease

2013-11-08 11:17 閱讀:1273 來源:愛愛醫(yī) 作者:7****i 責(zé)任編輯:78322li
[導(dǎo)讀] 【專家課件】 HodgkinDisease 內(nèi)容預(yù)覽: (點擊下圖可對專家課件進行全文預(yù)覽) 【專家課件】 HodgkinDisease 內(nèi)容簡介: HodgkinDisease Definition: neoplasticdisorderwithdevelopmentofspecificinfiltratecontainingpathologicReed-Sternbergcells.Itus

Hodgkin Disease 內(nèi)容預(yù)覽: 

(點擊下圖可對專家課件進行全文預(yù)覽)

Hodgkin Disease 內(nèi)容簡介:

HodgkinDisease
Definition:
neoplasticdisorderwithdevelopmentofspecificinfiltratecontainingpathologicReed-Sternbergcells.Itusuallyarisesinlymphnodesandspreadstocontiguousgroups.Extranodalpresentationarerare.Diseaseisassociatedwithdefectivecellularimmunity.

HodgkinDisease
Incidence:

-2-4casesper100000population/year
-bimodalagedistribution:
15-35yearsandabove50years
-malepredominanceM:F=1,7:1

ClinicalPresentation
Nontenderlymphnodesenlargement(localised)
neckandsupraclaviculararea60-80%
mediastinaladenopathy50%
other(abdominal,extranodaldisease)
systemicsymptoms(Bsymptoms)30%
fever
nightsweats
unexplainedweightloss(10%per6months)
othersymptoms
fatigue,weakness,pruritus
cough,chestpain,shortnessofbreath,venacavasyndrome
abdominalpain,boweldisturbances,ascites
bonepain

DiagnosisofHodgkinDisease
isbasedonmicroscopicexaminationoflymphnodeorotherinvolvedtissue
itrequiresidentificationofdiagnosticReed-Sternbergcells

PathologicClassification
WHO
ClassicalHodgkindisease
lymphocyterich(LR)
nodularsclerosis1and2(NS)
mixedcellularity(MC)

Hodgkin Disease ***下載


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